Platelet rich plasma treatment in Lahore Pakistan is offered at our clinic. This treatment has emerged as an effective therapy for all types of hair loss, especially androgenetic alopecia. It is also called FPHL and it influences approximately 50% of women especially those who are aged and enter their menopause phase. The etiological factors are both environmental and genetic. Androgenetic alopecia not only causes baldness but also disturbed the person psychologically and emotionally. Therefore, it is important to develop a safe, effective, and economical method of treatment and in this regard, PRP emerges as an effective, safe, and economical remedy for androgenetic alopecia. The PRP is prepared by the centrifugation of plasma in which in the first step red blood cells are separated and then again centrifugation is performed to concentrate platelets which are then used to make a suspension with a small volume of plasma. Because in this method platelets are extracted from the same person who is undergoing treatment, there are fewer chances of any infection or rejection by the immune system. In addition to the centrifugation method, there are also many other methods for the preparation of PRP such as the use of commercial kits, use of instruments that decrease white blood cell count and concentration of thrombocytes, etc. All of these methods result in the formation of suspension that contains different concentrations of both thrombocytes and platelets. But during the preparation of PRP, the protocol of preparation must be followed and i.e., blood is always collected with an anticoagulant (e.g., citrate) to avoid the clotting of blood and activation of thrombocytes. Then centrifugation of whole blood is performed immediately to separate red blood cells and then again to concentrate thrombocytes. Some protocols also include the insertion of thrombocyte activators from outside such as calcium chloride that cause an immediate release of growth factors (GFs) before being injected into the patient but there is no evidence of consent whether it increases the effectiveness of therapy or not. We are performing platelet rich plasma treatment in Lahore Pakistan by using activators so that immediate release of growth factors and quick improvement in the condition.
The first treatment was performed on 14th April 2022 at our clinic
Best clinic for Platelet rich plasma treatment Lahore Pakistan
Platelet-rich plasma hair loss treatment is used worldwide as such a substance that when injected in the body it promotes healing. That’s why many doctors use its injections to promote the growth of HFs in patients with alopecia both male and female. This solution when inserted into the scalp of the patient, the thrombocytes present in it becomes activated and start releasing various growth factors, which in return increase the growth of HFs. These growth factors not only enhance the growth of HFs but also activate the fibroblastic cells, synthesize collagen protein and ECM, and also increase the gene expression of endogenous GFs. All growth factors adding those that are released from platelets activate TGF-beta, VEGF, EGF, and IGF-1. These growth factors are also released from activated thrombocytes in this solution. All these factors work together and enhance the cell growth, differentiation, formation of new blood vessels, and movement of cells in response to a chemical stimulus. All of these functions are essential for the growth and formation of new HFs. Such as the insulin-like growth factor-1 increases the duration of the anagen phase (the phase in which new HFs grow). In granules of thrombocytes, many bioactive compounds are also present that increase the permeability of membranes and reduce inflammation. From many studies, it was found that insertion of this solution increases the growth of dermal papilla cells and also activates the signaling molecules such as kinases that are present in the extracellular matrix and protein kinase B. Both of these signaling molecules help in the proliferation of DP cells. It was believed that this solution influences the growth of HFs by increasing the duration of the anagen phase and by decreasing the apoptosis and duration of the catagen phase. This suspension also causes new blood vessels formation and follicular formation by acting on the raised area of follicles present in the stem cells. In addition to these functions, this solution also enhances the expression of beta-catenin which increases the growth of dermal papilla cells and causes the formation of new blood vessels. Thus, this solution increases the growth of HFs by causing the formation of new blood vessels in follicles, decreasing apoptosis, increasing the duration of the anagen phase, and by the faster transformation from telogen to anagen phase in dermal papilla cells.
In platelet-rich plasma hair loss treatment in Lahore Pakistan, PRP has been classified by many researchers. The classification of PRP was promoted to facilitate its administration and to compare the different researches and their effectiveness. It is a broad term that does not differentiate between different properties such as the concentration of platelets present in plasma, whether granulocytes are present or not, and other properties that influence the growth of HFs. A researcher classified it based on the existence of granulocytes, activity level, and concentration of thrombocytes in contrast to the whole blood. Because of this classification and after the publication of this classification particular characteristics of it had been recognized and high thrombocytes concentration solution had been produced. For this preparation, a double spin method was produced that prepares highly thrombocytes concentrated plasma (contain greater than 5 times concentration of thrombocytes as compared to whole blood) and contain a small number or zero red blood cells and white blood cells. Some researchers also classified it based on the presence or absence of white blood cell and thrombocyte concentration and the existence of fibrin protein. Currently, synthetically present are P-PRP, L-PRP, P-PRF. Moreover, the dose that is administered is measured by multiplying the concentration of thrombocytes with the volume of this solution, and the inserted dose is calculated in millions or billions. The effectiveness of this solution depends upon the percentage of thrombocytes retrieved in PRP from blood samples. The purification of this solution depends upon the concentration of thrombocytes, white blood cells, and erythrocytes. Classification based on activity was dependent upon if any thrombocyte activator is added or not such as thrombin, calcium chloride, and gluconate.
PRP treatment effectiveness
Thus, many studies have illustrated the effectiveness of Platelet-rich plasma hair loss treatment. The effectiveness of this test is evaluated by assessing different outcomes such as by assessing the outcome of hair pull test, photography before and after treatment, the average density of HFs, the ratio of anagen to telogen, and survey of patient’s satisfaction. The results of this therapy have mostly appeared after three months of therapy and the small after effect of this therapy was pain at the site of injection which is temporary. This therapy does not have adverse after-effects. Clinically, this therapy is recommended in combination with the topical use of drugs such as minoxidil and finasteride for the patients of androgenetic alopecia because this therapy alone is not able to deactivate the hormone that causes androgenetic alopecia and most clinicians recommended preparing this solution by using a single spin centrifugation method so, this solution is prepared with a concentration of thrombocytes 3 to 6 times more as compared to whole blood with a minimum amount of white blood cells. Many researchers also recommended that it is better to add a thrombocyte activator in this solution before administration to increase the release of growth factors and the solution is injected in the subdermal layer of skin because it is less painful. Moreover, the monthly follow-ups are arranged for the first three months and after every 3 months in the first year of therapy and many studies proved that both male and female patients have positive outcomes after receiving this therapy.
I washed my hair after 4 hours of my PRP treatment. I didn’t know about the 24 hours gap. Will it affect my treatment?
Can PRP hair treatment regrow hair?
What is platelet rich plasma treatment cost in Lahore Pakistan?
PRP hair treatment cost is 8000 Rs to 15000 Rs per session. There is price variation due to use of different types of kits, growth factors or vitamins in these kits.
Best Platelet rich plasma hair treatment in Lahore Pakistan?
Dr. Ahmad Chaudhry is foreign qualified, trained, experienced specialist in Pakistan and you will get the best treatment from his clinic. Whether this treatment will help you or not? You can send your head close up photos through WhatsApp +92-333-430-9999
If you are searching for the best platelet rich plasma treatment in Pakistan then our clinic is Number # 1 in the country where latest , disposable and state of the art equipment and kits are used for this purpose under the supervision of a highly trained , foreign qualified specialist Dr. Ahmad Chaudhry. If any of your relatives or friends are suffering from hair fall or thinning of hair then you can forward all the above information to platelet rich plasma treatment in Pakistan from our clinic.
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